The Napa Medical Research Foundation (NMRF), an independent 501(c)(3) non-profit foundation, funds a number of research projects for the Bodor Clinic. The goal of the NMRF is to conduct clinical and basic science research on the prevention, diagnosis, treatment and cure of conditions affecting nerves, muscles, bones and joints in adults and children and disseminate its findings within the medical profession and target populations to benefit the public good. For more information, visit www.napamedicalresearch.org.
The intervertebral disc is the primary cause if not the contributing factor to most chronic back pain. In our lab in 2019, we identified the optimum composition and concentration of PRP to stimulate proliferation and differentiation of human mesenchymal stem cells and production of hyaluronic acid in pig nucleus pulposus. Our paper has been published in Spine Journal: https://pubmed.ncbi.nlm.nih.gov/32565315/
We developed a technique for injecting platelets or mesenchymal stem cells into the cervical facet joints using ultrasound and without contrast dye, with greater accuracy than fluoroscopy (97% versus 91%, as confirmed by an independent radiologist). We have used this technique safely in over 7000 injections. We plan to publish our results in 2022.
We have developed a method for injecting bone marrow aspirate along the torn ends of the ACL to facilitate healing. We used this method in 5 patients and noted excellent functional outcomes and complete healing of at least one of the two bundles of the ACL in all 5. On the basis of this series, we have an IRB approved study in conjunction with UC Davis to study outcomes in a cohort of adults and children over the age of 12 treated with this technique.
Ultrasound Guided Surgery
We originally published a paper on a technique using ultrasound for visualization of the anatomy of the carpal tunnel, then inserting a micro-saw through the tunnel in order to release the transcarpal ligament: https://pubmed.ncbi.nlm.nih.gov/23417956/
Since then we have been following post-operative outcomes up to 1 year in patients treated with the Sonex device. Thus far our outcomes have demonstrated a very rapid postoperative recovery and excellent outcomes within several weeks, sustained at 1 year.
We have recently figured out a method for identifying the site of vaccine-deposition in patients with shoulder injury related to vaccine administration (SIRVA) and have been successful at resolving pain and restoring function in a series of 8 patients treated this way, using an ultrasound-guided ultrasonic aspiration and debridement method. The paper, describing outcomes in 5 consecutive patients, has been submitted for peer-review and publication.
In a series of patients with chronic pain following arthroplasty, we have been able to identify that small osteophytes can cause pain when they impinge on ligaments and tendons. We recently have been successful in using ultrasound-guided ultrasonic debridement to successfully reduce these osteophytes and resolve pain.